In accordance with the CARS 21 Communication (COM (2007) 0022), this Commission staff working document reports on the major automotive-related regulatory developments and activities that arose during 2010 at the World Forum for Harmonisation of Vehicle Regulations (“WP.29”) of the United Nations Economic Commission for Europe (“UNECE”). Its objective is to inform the European Parliament, the Council and the public about the progress achieved by WP.29 and of the compliance observed by the Commission with regards to the political orientations set out in the relevant EU legislation. This 2010 Commission staff working document is the fourth annual report on these activities.